Recombinant antibody and uses thereof
US10472411B2 · kind B2 · utility
1Cited by
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16Claims
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Key dates
| Filing date | May 13, 2019 |
| Grant date | Nov 12, 2019 |
| Priority date | — |
| Expiry date | May 13, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein is a phage-displayed single-chain variable fragment (scFv) library, that comprised a plurality of phage-displayed scFvs characterized with (1) a specific CS combination; (2) a specific distribution of aromatic residues in each CDR; and (3) a specific sequence in each CDR. The present scFv library could be used to efficiently produce different antibodies with binding affinity to different antigens. Accordingly, the present disclosure provides a potential means to generate different antigen-specific antibodies promptly in accordance with the need in experimental researches and/or clinical applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.