Antibodies specific for hyperphosphorylated tau and methods of use
US10472415B2 · kind B2 · utility
5Cited by
40References
3Claims
0Family size
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Key dates
| Filing date | Jul 10, 2017 |
| Grant date | Nov 12, 2019 |
| Priority date | — |
| Expiry date | Jul 10, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2821
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.