Patent · US Active

Human PAC1 antibodies

US10472417B2 · kind B2 · utility

0Cited by

9References

15Claims

0Family size

Assignee

AMGEN INC. · US

Inventors

Cen Xu · Newbury Park, US
Agnes Eva Hamburger · Newbury Park, US

Key dates

Filing date	Jun 25, 2018
Grant date	Nov 12, 2019
Priority date	—
Expiry date	Jun 25, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Antibodies and antigen-binding fragments thereof that bind to human PAC1 are provided. Nucleic acids encoding the antibodies and antigen-binding fragments thereof, vectors, and cells encoding the same are also provided. The antibodies and antigen-binding fragments thereof can inhibit binding of PAC1 to PACAP, and are useful in a number of PAC1 related disorders, including the treatment and/or prevention of headache disorders, including migraine and cluster headache.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.