Method for modulating car-induced immune cells activity
US10472613B2 · kind B2 · utility
5Cited by
0References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 7, 2015 |
| Grant date | Nov 12, 2019 |
| Priority date | — |
| Expiry date | Jun 25, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method to modulate the level of activation of an engineered immune cell (such as a Chimeric Antigen Receptor T-cell) for immunotherapy. The present invention also relates to cells obtained by the present method, preferably comprising said modulable/tunable chimeric antigen receptors for use in therapeutic or prophylactic treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.