Methods for tissue passivation

US10478284B2 · kind B2 · utility

Assignee

• The General Hospital Corporation · US

Inventors

• William G. Austen · Weston, US
• Michael McCormack · Medford, US
• Robert W. Redmond · Newton, US
• Irene E. Kochevar · Boston, US

Key dates

• Filing date: Jan 20, 2015
• Grant date: Nov 19, 2019
• Expiry date: Jan 20, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N5/0624
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods of tissue passivation are described herein for use in preserving normal tissue architecture, reducing post-surgical inflammation, and reducing or preventing the development of pathogenic collagen bundles and adhesions following surgical procedures. Passivated tissues prepared in accordance with these methods are useful in a variety of therapies including, e.g., cardiac bypass surgery, hemodialysis, etc.