[1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds

US10478424B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Alaric J. Dyckman · Lawrenceville, US
• Dharmpal S. Dodd · Princeton, US
• Christopher P. Mussari · Princeton, US
• Laxman Pasunoori · Warangal, IN
• Sreekantha Ratna Kumar · Bengaluru, IN

Key dates

• Filing date: Jul 23, 2018
• Grant date: Nov 19, 2019
• Expiry date: Jul 23, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are compounds of Formula (I) or a salt thereof, wherein R1, R2, R3, R4, R5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.