Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents

US10479765B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Hartmut Beck · Wuppertal, DE
• Tobias Thaler · Neunburg vorm Wald, DE
• Raimund Kast · Wuppertal, DE
• Daniel Meibom · Leverkusen, DE
• Mark Meininghaus · Wuppertal, DE
• Carsten TERJUNG · Bochum, DE
• Martina Delbeck · Essen, DE
• Klemens Lustig · Wuppertal, DE
• Uwe Muenster · Wuppertal, DE
• Britta Olenik · Bottrop, DE

Key dates

• Filing date: Sep 7, 2018
• Grant date: Nov 19, 2019
• Expiry date: Sep 7, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel substituted N,2-diarylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and/or inflammatory disorders.