RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
US10479992B2 · kind B2 · utility
25Cited by
266References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 30, 2017 |
| Grant date | Nov 19, 2019 |
| Priority date | — |
| Expiry date | Jun 30, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/51
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to RNAi constructs and their use in gene silencing. RNAi constructs associated with the invention contain a double stranded region connected to a single stranded region of phosphorothioate modified nucleotides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.