Patent · US Active

Nanopore sequencing using n-mers

US10481144B2 · kind B2 · utility

6Cited by

20References

19Claims

0Family size

Assignee

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. · US

Inventors

Stephen Turner · Menlo Park, US
Benjamin Flusberg · Atlanta, US

Key dates

Filing date	Jul 19, 2017
Grant date	Nov 19, 2019
Priority date	—
Expiry date	Feb 26, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2565/631
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates to devices and methods for nanopore sequencing. The invention provides devices having an array of nanopores. The devices comprise an upper fluidic region in fluidic contact with the nanopores. The upper fluidic region comprises and upper electrode. Below each nanopore, and in fluidic contact with each nanopore is a discrete fluidic region. There is no direct fluidic contact between these discrete fluidic regions. The devices have an advantage of lower levels of electrical cross-talk between nanopores in the array for improved nucleic acid sequencing.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.