Detection of autoantibodies reactive with pancreatic islet cell antigenic molecules and/or insulin
US10481156B2 · kind B2 · utility
0Cited by
7References
34Claims
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Key dates
| Filing date | Aug 19, 2016 |
| Grant date | Nov 19, 2019 |
| Priority date | — |
| Expiry date | May 1, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/042
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of screening a sample of body fluid obtained from an animal subject for analyte autoantibodies reactive with one or more antigenic molecules selected from pancreatic islet cell antigenic molecules (GAD, 1A2) and insulin, or one or more variants, analogs, derivatives or fragments thereof, and a kit for use in such a method. After addition of the sample one or more complexes comprising [antigenic molecule of first source]-[analyte auto antibody]-[antigenic molecule of second source]. The antigenic molecule of first source is immobilized to a solid phase, the second is labeled.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.