Quantification of local circulation with OCT angiography
US10485423B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 25, 2016 |
| Grant date | Nov 26, 2019 |
| Priority date | — |
| Expiry date | Dec 12, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30104
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Impaired intraocular blood flow within vascular beds in the human eye is associated with certain ocular diseases including, for example, glaucoma, diabetic retinopathy and age-related macular degeneration. A reliable method to quantify blood flow in the various intraocular vascular beds could provide insight into the vascular component of ocular disease pathophysiology. Using ultrahigh-speed optical coherence tomography (OCT), a new 3D angiography algorithm called split-spectrum amplitude-decorrelation angiography (SSADA) was developed for imaging microcirculation within different intraocular regions. A method to quantify SSADA results was developed and used to detect perfusion changes in early stage ocular disease. Associated embodiments relating to methods for quantitatively measuring blood flow at various intraocular vasculature sites, systems for practicing such methods, and use of such methods and systems for diagnosing certain ocular diseases are herein described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.