Vacuum-loaded, droplet-generating microfluidic chips and related methods
US10486155B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 18, 2019 |
| Grant date | Nov 26, 2019 |
| Priority date | — |
| Expiry date | Jan 18, 2039 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/049
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A microfluidic chip that can have a body defining a microfluidic network including a test volume, one or more ports, and one or more channels in fluid communication between the port(s) and the test volume is described. Gas can be removed from the test volume before a sample liquid is introduced therein by reducing pressure at a first one of the port(s), optionally while the liquid is disposed in the port. Liquid in the first port can be introduced into the test volume by increasing pressure at the first port. The microfluidic network can define one or more droplet-generating regions in which at least one of the channel(s) defines a constriction and/or two or more of the channels connect at a junction. Liquid flowing from the first port can pass through at least one of the droplet-generating region(s) and to the test volume.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.