Frequency domain fluorescence measurement system
US10488339B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 5, 2019 |
| Grant date | Nov 26, 2019 |
| Priority date | — |
| Expiry date | Mar 5, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/061
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Apparatuses, methods, and computer program products for analyzing target compounds. An excitation signal comprising light having a time-varying intensity is transmitted into a target compound. In response to receiving the excitation signal, the target compound generates an emission signal. To increase the intensity of the emission signal, a fluorophore may be provided to the target compound. The fluorophore may be configured to react with a characteristic of the target compound so that the fluorophore generates the emission signal in response to the presence of both the characteristic and the excitation signal. The emission signal may be compared to the excitation signal in a frequency domain to determine a phase of the emission signal relative to the excitation signal. The phase may be used to determine a luminescence lifetime of the emission signal. If the detected luminescence lifetime matches an expected luminescence lifetime, the target compound likely includes the characteristic.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.