Porous particles for liquid chromatography and processes for the preparation thereof
US10493428B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Nov 22, 2012 |
| Grant date | Dec 3, 2019 |
| Priority date | — |
| Expiry date | Aug 29, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC01P2006/16
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Superficially porous silica particles are provided as well as a one-pot process for making the superficially porous particles, the process comprising hydrolyzing and condensing a silica precursor comprising a functional group to form superficially porous particles, the superficially porous particles comprising silica microparticles having silica nanoparticles bound to the surface of the microparticles. The nanoparticles provide a porous outer layer on the microparticles. The superficially porous particles are useful as a stationary phase in liquid chromatography and allow for fast mass transfer and separation of samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.