Patent · US Active

(20S)-1-α,25-dihydroxy-24,24-difluoro-19-nor-vitamin D3 analogs and their pharmaceutical uses

US10494337B2 · kind B2 · utility

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0References

9Claims

0Family size

Assignee

Wisconsin Alumni Research Foundation · US

Inventors

Hector F. DeLuca · Deerfield, US
Agnieszka Flores · Madison, US
Lori A. Plum · Madison, US
Hazel Holden · Fitchburg, US
James B. Thoden · Madison, US

Key dates

Filing date	May 26, 2016
Grant date	Dec 3, 2019
Priority date	—
Expiry date	May 26, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2602/24
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed are 1α,25-dihydroxy-24,24-difluoro-2-methylene-19-nor-vitamin D analogs and their pharmaceutical uses. These new vitamin D analogs are 19-nor-vitamin D analogs having two fluorine atom substitutions at the 24 position (C-24) in the side chain and optionally having a 2-methylene substituent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.