6-oxa-3,9,15-triaza-bicyclo[9.3.1]pentadeca-1(14),11(15),12-triene derivatives based compounds and their application as ligands of essential metal ion based MRI and 52MN based PET contrast agents
US10494379B2 · kind B2 · utility
1Cited by
5References
20Claims
0Family size
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Key dates
| Filing date | Nov 25, 2016 |
| Grant date | Dec 3, 2019 |
| Priority date | — |
| Expiry date | Nov 25, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K51/0482
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The one subject of the invention is the compounds of general formula (I), their isomers, their physiologically acceptable salts and/or Mn(II), Fe(II), Fe(III), Co(II) and Ni(II) complexes and their application: where R1|=—OH or —NR3R4 amide functionality.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.