Patent · US Active

Multiloop engineered heart muscle tissue

US10494605B2 · kind B2 · utility

0Cited by

0References

10Claims

0Family size

Assignee

Tissue Systems Holding GmbH · DE

Inventors

Wolfram-Hubertus Zimmermann · Göttingen, DE
Thomas Eschenhagen · Hamburg, DE

Key dates

Filing date	Mar 26, 2018
Grant date	Dec 3, 2019
Priority date	—
Expiry date	Mar 26, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2506/02
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention is directed to a method for the preparation of a multiring engineered heart tissue construct suitable for use in cardiac tissue augmentation and/or replacement therapy. The invention further refers to multiring EHT constructs which comprise at least two force-generating engineered heart tissue rings fused with each other and a device for preparing the same. Finally, the invention relates to force-generating engineered heart tissue rings derived human cells and their use in drug screening and target validation assays.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.