Method of determining dose of erythropoiesis-stimulating agent
US10496794B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 7, 2015 |
| Grant date | Dec 3, 2019 |
| Priority date | — |
| Expiry date | Feb 19, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16C20/30
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of determining an ESA dose, which allows a hemoglobin concentration in the blood to be stably maintained at a target value, and which can decrease a range of fluctuation of the hemoglobin concentration with respect to the target value. The method comprises the steps of: setting the target value of the hemoglobin concentration in the blood; calculating a target value of a hemoglobin production rate which allows the hemoglobin concentration to reach the target value; calculating a serum ESA concentration which allows the hemoglobin production rate to reach the target value, from a relationship between the hemoglobin production rate and the ESA concentration; and calculating an amount of administration of an ESA which gives the serum ESA concentration, from a relationship between the ESA concentration and the amount of administration of the ESA, to determine an ESA dose which allows the hemoglobin concentration to reach the target value.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.