Patent · US Active

Automated percentage of breast density measurements for full field digital mammography

US10497117B2 · kind B2 · utility

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Key dates

Filing dateMay 24, 2018
Grant dateDec 3, 2019
Priority date
Expiry dateMay 24, 2038

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG06V2201/03
  • WIPO fieldComputer technology
  • WIPO sectorElectrical engineering

Abstract

An automated percentage of breast density measure (PDa) that analyzes signal dependent noise (SDN) based on a wavelet expansion using full field digital mammography (FFDM). A matched case-control dataset is used with images acquired from a specific direct x-ray capture FFDM system. PDa is applied to the raw and clinical display representation images. Transforming (pixel mapping) of the raw image to another representation (raw-transformed) is performed using differential evolution optimization and investigated the influence of lowering the native spatial resolution of the image by a one-half. When controlling for body mass index, the quartile specific ORs for the associations of PDa with breast cancer varied with representation and resolution. PDa is a valid automated breast density measurement for a specific FFDM technology and compares well against PD (operator-assisted or the standard) when applied to either the raw-transformed or clinical display images from this FFDM technology.

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