Patent · US Active

Compositions and methods for treating bone, joints and cartilage

US10500233B2 · kind B2 · utility

0Cited by
13References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 12, 2015
Grant dateDec 10, 2019
Priority date—
Expiry dateMay 25, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N5/0627
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Briefly stated, the present invention provides compositions and methods for treating or preventing joint injuries utilizing hair follicle derived Non-Bulbar Dermal Sheath (“NDBS”) cells. Within one aspect of the invention methods are provided for isolating NBDS cells, comprising the steps of: (a) preparing vital hair; (b) cleaving the hair prepared in step (a) to remove the hair follicle bulb; (c) isolating Non-Bulbar Dermal Sheath tissue; and (d) cultivating the isolated Non-Bulbar Dermal sheath tissue to produce NBDS cells. Within one embodiment of the invention the vital hair is obtained by full skin biopsy from the occipital scalp of a subject.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.