Device and method for a nanofiber wrap to minimize inflamation and scarring
US10500305B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Apr 9, 2015 |
| Grant date | Dec 10, 2019 |
| Priority date | — |
| Expiry date | Dec 13, 2035 |
Classification
- Technology area (CPC D)Textiles; Paper
- CPC primaryD10B2509/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention is directed to a device and method for a nanofiber wrap to minimize inflation and scarring of nerve tissue and maximize the nutrient transport. More particularly, the present invention is directed to a novel semi-permeable nanofiber construct prepared from biocompatible materials. The nanofiber construct is applied around a nerve repair site following end-to-end anastomosis. The nanofiber construct is porous and composed of randomly oriented nanofibers prepare using an electrospinning method. The nanofiber construct has a wall that is approximately 50-100 μm thick with pores smaller than 25 μm. The nanofiber construct prevents inflammatory cells from migrating into the nerve coaption site, while still permitting the diffusion of growth factors and essential nutrients. The nanofiber construct allows for enhanced neuroregeneration and optimal function outcomes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.