Substituted benzimidazoles as modulators of Ras signaling
US10501421B1 · kind B1 · utility
1Cited by
3References
16Claims
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Key dates
| Filing date | Jan 27, 2017 |
| Grant date | Dec 10, 2019 |
| Priority date | — |
| Expiry date | Jan 27, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Benzimidazole compounds that increase the rate of SOS-mediated nucleotide exchange on Ras by binding to a functionally relevant, chemically tractable pocket on the SOS protein, as part of the Ras:SOS:Ras complex.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.