Aryl-substituted dihydroquinolinones, their preparation and their use as pharmaceuticals
US10501438B2 · kind B2 · utility
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5References
25Claims
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Key dates
| Filing date | Aug 11, 2016 |
| Grant date | Dec 10, 2019 |
| Priority date | — |
| Expiry date | Aug 11, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This application relates to aryl-substituted dihydroquinolinones of formula (I), compositions comprising them and their uses in the treatment of diseases and conditions in which inhibition of a bromodomain is indicated. For example, the application relates to aryl-substituted dihydroquinolinones and to their use as bromodomain inhibitors. The present application is also related to the treatment or prevention of proliferative disorders, auto-immune disorders, inflammatory disorders, dermal disorders, and neoplasms, including tumors and/or cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.