Patent · US Active

Monocyclic β-lactam-siderophore conjugate, and preparation method and use thereof

US10501454B2 · kind B2 · utility

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1References

11Claims

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Assignee

SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES · CN

Inventors

Yushe Yang · Shanghai, CN
Liang Tan · Shanghai, CN
Qunhuan Kou · Shanghai, CN

Key dates

Filing date	Jan 18, 2019
Grant date	Dec 10, 2019
Priority date	—
Expiry date	Jan 18, 2039

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure relates to the field of pharmaceutical synthesis, and more particularly, relates to a monocyclic β-lactam-siderophore conjugate as well as a method for synthesizing same and its use in the treatment of bacterial infectious diseases. Provided are a monocyclic β-lactam-siderophore conjugate represented by formula (I) as described herein, an optical isomer thereof or a pharmaceutically acceptable salt thereof, and a method for synthesizing same, and a use thereof in treating bacterial infectious diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.