Patent · US Active

Tyrosine amide derivatives as Rho-kinase inhibitors

US10501461B2 · kind B2 · utility

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Assignee

Inventors

Key dates

Filing dateJan 30, 2018
Grant dateDec 10, 2019
Priority date—
Expiry dateMar 5, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Tyrosine amide compounds of formula I described herein inhibit Rho Kinase and may be used for the treatment of many disorders associated with ROCK enzymes mechanisms, such as pulmonary diseases including asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.