Conotoxin peptide κ-CPTx-BTL01, preparation method therefor, and uses thereof
US10501498B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 26, 2014 |
| Grant date | Dec 10, 2019 |
| Priority date | — |
| Expiry date | Feb 3, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K17/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a new conotoxin peptide κ-CPTx-bt101. The conotoxin peptide κ-CPTx-bt101 has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1, or has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1 and that is formed after substitution, addition or deletion of one or more amino acids are performed and has original functions. Also provided is polynucleotide for coding the peptide, comprising a constructed body of the polynucleotide, an expression carrier and transformed cells. A peptide preparation method and uses in the treatment of diseases related to a calcium ion channel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.