Patent · US Active

Method and kit for prognosis of OPA1 gene induced diseases, E.G. Kjers optic atrophy

US10501798B2 · kind B2 · utility

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Key dates

Filing dateMar 27, 2015
Grant dateDec 10, 2019
Priority date
Expiry dateJan 8, 2036

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/16
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Providing Nuclear factor (erythroid-derived 2)-like 2 (NRF2)-activated genes products, e.g. SOD1 and CAT, in their use in the prognosis of an OPA1 gene- or OPA1 gene product-deficit-induced disease, or related complications, e.g. optic atrophy and optic neuropathy, in a biological sample selected from fibroblasts, epithelial cells, blood samples or a mixture thereof, of a patient affected or suspected to be affected by the disease.

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