Systems and methods using biomarker panel data

US10502747B2 · kind B2 · utility

Assignees

• Cardiac Pacemakers, Inc. · US
• MUSC Foundation for Research Development · US

Inventors

• Craig Stolen · New Brighton, US
• Timothy Edward Meyer · North Oaks, US
• Milan Seth · Minneapolis, US
• Francis G. Spinale · Charleston, US
• Nicholas Wold · Arden Hills, US

Key dates

• Filing date: Jan 31, 2013
• Grant date: Dec 10, 2019
• Expiry date: Nov 27, 2033

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/52
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Embodiments of the disclosure are related to systems and methods for utilizing biomarker panel data with respect to medical devices and methods, amongst other things. In an embodiment, the disclosure can include a method of predicting the likelihood of response to CRT therapy. The method can include quantifying levels of one or more biomarkers in a biological sample of a patient, analyzing the quantified levels to determine response to CRT therapy, wherein a panel of biomarkers includes at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4. Other embodiments are also included herein.