Pyrimidopyrrole compounds, method for preparing the same, pharmaceutical compositions comprising the same and uses thereof

US10508118B2 · kind B2 · utility

Assignee

• XIAMEN UNIVERSITY · CN

Inventors

• Xianming Deng · Fujian, CN
• Zhongji Zhuang · Fujian, CN
• Zhou Deng · Beijing, CN
• Xiaoxing Huang · Fujian, CN
• Yan Liu · Tangshan City, CN
• Ting Zhang · Shanghai, CN
• Wei-Jan Huang · Taipei, TW
• Qingyan Xu · Xiamen, CN
• Zhiyu Hu · Beijing, CN

Key dates

• Filing date: Apr 25, 2016
• Grant date: Dec 17, 2019
• Expiry date: Apr 25, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/6561
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a compound of formula I, a stereoisomer, a prodrug, a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable solvate thereof, and a process for preparing the same, a pharmaceutical composition comprising the same, and use of the compound in the preparation of medicine preventing and treating tumors, wherein the substituents are as defined in the specification.