Antibodies, antibody drug conjugates and methods of use
US10509035B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 5, 2016 |
| Grant date | Dec 17, 2019 |
| Priority date | — |
| Expiry date | Aug 5, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/72
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to antibody drug conjugates (ADC), antibody conjugates (AC) and novel antibodies. Particularly, the ADC, AC and antibodies disclosed herein specifically bind to the human anti-Müllerian hormone type II receptor (AMHR-II) and can be used to treat and/or identify AMHR-II expressing cancers, such as prostate cancer, breast cancer and gynecologic cancers expressing AMHR-II, such as ovarian cancer, in particular metastatic ovarian cancer, serous cancer, hypernephroma, endometrioid, colloidal epithelium, prostate cancer, germ cell cancer, endometrial cancer, mixed Müllerian malignant tumor of the uterus, leiomyosarcoma, or endometrial stromal sarcoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.