Processes for the preparation of apalutamide and intermediates thereof
US10513504B2 · kind B2 · utility
1Cited by
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19Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 6, 2019 |
| Grant date | Dec 24, 2019 |
| Priority date | — |
| Expiry date | Mar 6, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides processes for the preparation of Apalutamide (1), as well as intermediates useful in the preparation thereof. In particular, the process of the invention utilizes the intermediate compound of Formula (2), wherein G is OH or a leaving group, which provides improvements over the known processes for the preparation of Apalutamide (1).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.