Self-replication of nucleic acid origami tiles
US10513535B2 · kind B2 · utility
5Cited by
0References
17Claims
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Key dates
| Filing date | Oct 26, 2015 |
| Grant date | Dec 24, 2019 |
| Priority date | — |
| Expiry date | Jun 3, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6816
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a method for self-replication of multimers of nucleic acid origami tiles by exponentially amplifying the multimer from initial seeds of monomeric units of nucleic acid origami tiles and also provides for the selective exponential amplification of a designated multimer, such as with specific properties or characteristics, over one or more competing multimers in the presence of a mixture of monomers for each of the possible multimers. The selection of the designated multimer based on an environmental change allows the designated multimer to outgrow all competing multimers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.