Anti-ASIC1 antibodies and uses thereof
US10513557B2 · kind B2 · utility
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10References
27Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 28, 2017 |
| Grant date | Dec 24, 2019 |
| Priority date | — |
| Expiry date | Sep 28, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides antibodies and antigen-binding fragments thereof that specifically bind to cells expressing acid-sensing ion channel-1 (ASIC1). According to certain embodiments of the invention, the antibodies inhibit acid-induced, ASIC1-mediated ion currents in cells expressing human ASIC1. The antibodies of the invention are useful for the treatment of pain, including pain associated with surgical intervention and various diseases and disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.