Pegylated carfilzomib compounds
US10517954B2 · kind B2 · utility
1Cited by
1References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 23, 2017 |
| Grant date | Dec 31, 2019 |
| Priority date | — |
| Expiry date | Jan 31, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G2230/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides polymeric pegylated carfilzomib compounds, and pharmaceutically acceptable salts thereof, of Formula I wherein R1, R2, linker, PEG, n and o are as defined herein. The invention also provides methods of making and using these compounds to treat cancer, and particularly to treat hematological malignancies including multiple myeloma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.