Cyclic di-nucleotide compounds and methods of use

US10519188B2 · kind B2 · utility

Assignees

• ImmuneSensor Therapeutics, Inc. · US
• The Board of Regents of the University of Texas System · US

Inventors

• Boyu Zhong · Carmel, US
• Lijun Sun · Harvard, US
• Heping Shi · Dallas, US
• Qi Wei · Dallas, US
• Yuanwei DAI · Dallas, US
• Chuo Chen · Dallas, US
• Zhijian Chen · Dallas, US

Key dates

• Filing date: Apr 15, 2018
• Grant date: Dec 31, 2019
• Expiry date: Apr 15, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H21/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are cyclic-di-nucleotide cGAMP analogs, methods of synthesizing the compounds, pharmaceutical compositions comprising the compounds thereof, and use of compounds and compositions in medical therapy.