Methods and systems for rapid detection of microorganisms using infectious agents
US10519483B2 · kind B2 · utility
8Cited by
7References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 18, 2015 |
| Grant date | Dec 31, 2019 |
| Priority date | — |
| Expiry date | Nov 19, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2795/10243
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are methods and systems for rapid detection of microorganisms in a sample, without culturing for enrichment of the microorganism. A modified bacteriophage is also disclosed which comprises a non-native indicator gene in the late gene region. The indicator product is not a fusion protein. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.