Digital sequence analysis of DNA methylation
US10519510B2 · kind B2 · utility
8Cited by
63References
16Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 28, 2016 |
| Grant date | Dec 31, 2019 |
| Priority date | — |
| Expiry date | Jul 9, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/154
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to methods and compositions for determination of and uses of specific methylation patterns indicative of adenoma and carcinoma. In particular, the invention relates to analysis of defined CpG loci that are coordinately methylated in DNAs from cancer and adenoma samples, methods for identifying coordinately methylated loci, and methods of using analysis of coordinately methylated loci in one or more marker regions in the design of assays for adenoma and cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.