Patent · US Active

Small molecule binding pockets in nucleic acids

US10522239B2 · kind B2 · utility

0Cited by

3References

15Claims

0Family size

Assignee

Nymirum, Inc. · US

Inventors

Andrew Corbet Stelzer · Ann Arbor, US
Mitchell Alan McBrairty · Ann Arbor, US
Hashim M. Al-Hashimi · Ann Arbor, US
Sung-Hun Bae · Čadca, SK

Key dates

Filing date	Sep 1, 2016
Grant date	Dec 31, 2019
Priority date	—
Expiry date	Sep 17, 2037

Classification

Technology area (CPC G)Physics
CPC primaryG16C20/60
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Described herein is technology for determining the 2-D or 3-D atomic resolution structure of a polynucleotide bound to and/or interacting with another molecule, for example a small molecule. In some aspects of the technology, NMR and isotopic labeling strategies are used. The technology described herein is useful for a plurality of applications including but not limited to drug discovery and chemical biology probe discovery.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.