Fluoroalkyl-substituted aryltriazole derivatives and uses thereof

US10525041B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Thomas Neubauer · Wuppertal, DE
• Marie-Pierre Collin-Kröpelin · Wuppertal, DE
• Peter Kolkhof · Wuppertal, DE
• Elisabeth Pook · Wuppertal, DE
• Matthias Beat WITTWER · Riehen, CH
• Klemens Lustig · Wuppertal, DE
• Carsten Schmeck · Wuppertal, DE
• Pierre Wasnaire · Mülheim an der Ruhr, DE
• Heiko Schirmer · Solingen, DE

Key dates

• Filing date: May 2, 2017
• Grant date: Jan 7, 2020
• Expiry date: May 2, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel 5-(fluoroalkyl)-1-aryl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.