Patent · US Active

ATF5 peptide variants and uses thereof

US10525100B2 · kind B2 · utility

0Cited by

16References

9Claims

0Family size

Assignee

Sapience Therapeutics, Inc. · DE

Inventors

Barry Jay Kappel · Pelham, US
Gene Merutka · Hillsborough, US
Jimmy Andrew Rotolo · New York, US

Key dates

Filing date	Jan 3, 2019
Grant date	Jan 7, 2020
Priority date	—
Expiry date	Jan 3, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/73
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are activating transcription factor 5 (ATF5) peptides having a truncated ATF5 leucine zipper region and, optionally, a cell-penetrating region, compositions comprising the ATF5 peptides, and methods of inhibiting proliferation of and promoting cytotoxicity in a neoplastic cell using the ATF5 peptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.