Conjugate of polyethylene glycol and anesthetic, and preparation method thereof
US10525143B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Dec 20, 2017 |
| Grant date | Jan 7, 2020 |
| Priority date | — |
| Expiry date | Dec 27, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A conjugate represented by general formula (I), wherein R0 is a C1-6 alkyl, B is an anesthetic, and A is a linking group, and a quaternary ammonium salt is formed at the linking position between B and R0. The conjugate has a prolonged analgesic effect, and can be used in postoperative analgesia or treatment for chronic pain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.