Disruption and field enabled delivery of compounds and compositions into cells
US10526573B2 · kind B2 · utility
12Cited by
26References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 13, 2015 |
| Grant date | Jan 7, 2020 |
| Priority date | — |
| Expiry date | Dec 13, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/87
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A microfluidic system for causing perturbations in a cell membrane includes (a) a microfluidic channel defining a lumen and configured such that a cell suspended in a buffer can pass there through, and (b) source or emitter of an energy field. The microfluidic channel may include a cell-deforming constriction. A diameter of the constriction may be a function of the diameter of the cell. Related apparatus, systems, techniques, and articles are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.