Patent · US Active

Method and microplate reader for investigating biological cells or cell cultures

US10527550B2 · kind B2 · utility

0Cited by

5References

18Claims

0Family size

Assignee

TECAN TRADING AG · CH

Inventors

Harald Gebetsroither · Grödig, AT
Andreas Gfrorer · Königsdorf, DE
Juha Koota · Berchtesgaden, DE

Key dates

Filing date	Mar 13, 2013
Grant date	Jan 7, 2020
Priority date	—
Expiry date	Mar 13, 2033

Classification

Technology area (CPC G)Physics
CPC primaryG01N2015/1486
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A method for investigating biological cells or cell cultures in a microplate reader receives at least one microplate with wells containing biological cells or cell cultures by a receiving device; positions the wells with respect to measuring devices of the microplate reader and detects integral measurement signals by at least one of the measuring devices. The biological cells or cell cultures in the specific wells of the microplate(s) are transilluminated by an illumination source of the microplate reader and imaged by an imaging camera. Each of the detected integral signals is compared with the image of the biological cells or cell cultures in the corresponding wells of the microplate(s) by a processor and is related to the imaged number, adherence, confluence or morphology of these biological cells or cell cultures.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.