Devices and methods of cell capture and analysis
US10527611B2 · kind B2 · utility
1Cited by
8References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 29, 2015 |
| Grant date | Jan 7, 2020 |
| Priority date | — |
| Expiry date | May 28, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/57492
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a device for isolating target biomolecules or cells from samples, particularly biological samples. In particular, the device comprises a loading mixture, which contains the biological sample and a first binding entity that specifically binds to the target biomolecule or target cell; and a micro-channel coated with a second binding entity that binds directly or indirectly to the first binding entity. Methods of capturing, detecting, and/or evaluating target biomolecules or target cells (e.g. cancer cells) in biological samples are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.