Modified demineralized cortical bone fibers

US10531957B2 · kind B2 · utility

Assignee

• Musculoskeletal Transplant Foundation · US

Inventors

• Michele Christine McAllister · Freehold, US
• David Huabin Wang · Beavercreek, US
• Michelle Bubear · Newton, US
• Joed Canales · Harrison, US
• Amy Chang · Kaneohe, US
• Roman Shikhanovich · Edison, US
• Mark Spilker · Plainsboro, US
• Eric J. Semler · Piscataway, US

Key dates

• Filing date: May 19, 2016
• Grant date: Jan 14, 2020
• Expiry date: May 19, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/38
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Surgical implants (or grafts) for the repair of bone defects, more particularly, surgical implants that include demineralized bone fibers, are disclosed. The surgical implants have a wettability time of less than 5 minutes and a residual moisture content of less than 6% by weight, and they remain cohesive and retain their shape upon complete rehydration. Methods for making such implants and for increasing their wettability and ensuring uniform density are also disclosed.