pH control for analyte detection
US10532356B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 9, 2017 |
| Grant date | Jan 14, 2020 |
| Priority date | — |
| Expiry date | Jan 31, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/4167
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Aspects of the present disclosure are directed to a pH control device. The device comprises a substrate, on which is defined a flow path adapted to receive a liquid. The device further comprises a set of electrodes, which includes a pH sensing electrode and pH generation electrodes. The electrodes are arranged along the flow path. The pH sensing electrode is arranged so as to be subjected to a change in pH of a portion of the liquid on the flow path, as caused by the pH generation electrodes. In addition, the device includes a controller, which is configured to apply a voltage across the pH generation electrodes, based on a signal obtained via the pH sensing electrode and a reference electrode. This enables local control a pH of the liquid portion. The device may further be embodied as a sensor, additionally comprising a detection electrode.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.