Substituted pyrazole compounds as serine protease inhibitors
US10532995B2 · kind B2 · utility
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37Claims
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Key dates
| Filing date | Feb 29, 2016 |
| Grant date | Jan 14, 2020 |
| Priority date | — |
| Expiry date | Feb 29, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin and/or kallikrein, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which diseases or disorders are amenable to treatment or prevention by the inhibition of thrombin and/or kallikrein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.