Patent · US Active

FMRI biomarker of neurodegenerative disease

US10534052B2 · kind B2 · utility

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20Claims
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Key dates

Filing dateMar 14, 2014
Grant dateJan 14, 2020
Priority date—
Expiry dateMar 26, 2037

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61B2576/026
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Provided herein are methods related to identifying an early, asymptomatic (prodromal) stage of a neurodegenerative disease or identifying a subject with a symptomatic neurodegenerative disease, including, for example, mild cognitive impairment (MCI), Alzheimer's Disease (AD), or HIV-associated neurocognitive disorder (HAND), using functional MRI data from the subject. Methods are also provided for treating a subject identified with the methods taught herein and for modifying or selecting treatment based on the results of fMRI. Methods are also available for staging neurodegenerative disease and for identifying agents useful in treating them.

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