Patent · US Active

Solid dosage forms comprising an enteric coating with accelerated drug release

US10537530B2 · kind B2 · utility

0Cited by

8References

4Claims

0Family size

Assignee

Evonik Operations GmbH · DE

Inventors

Fang-Wei Liu · London, GB
Abdul Waseh Basit · Harrow, GB
Rosario Lizio · Dieburg, DE
Hans-Ulrich Petereit · Darmstadt, DE
Christian Meier · Darmstadt, DE
Michael Damm · Rödermark, DE

Key dates

Filing date	Sep 5, 2012
Grant date	Jan 21, 2020
Priority date	—
Expiry date	Feb 12, 2035

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/5026
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides a gastric resistant, enteric-coated solid dosage form including a core containing a pharmaceutically active ingredient, an inner coating for the core, and an outer enteric coating. The inner coating comprises an anionic polymeric material or a water-soluble neutral polymeric material, and further comprises a water soluble inorganic salt which is not a carbonate or bicarbonates. The outer enteric coating comprises an anionic polymeric material which is less neutralized than the polymeric material comprising the inner coating and disintegrates rapidly at a pH of 5.5 to 7.0 upon entering the small intestine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.