Patent · US Active

Gas-filled microvesicles for use as vaccine

US10537622B2 · kind B2 · utility

1Cited by

7References

16Claims

0Family size

Assignee

Bracco Suisse SA · CH

Inventors

Gilles Bioley · Fiez, CH
Philippe Bussat · Cognac, FR
Blaise Corthesy · Cugy, CH
Anne Lassus · Veyrier, CH

Key dates

Filing date	Dec 21, 2015
Grant date	Jan 21, 2020
Priority date	—
Expiry date	Dec 21, 2035

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/6018
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Gas-filled microvesicles comprising an antigen bound thereto and to aqueous suspensions containing said microvesicles, for use in immunomodulating formulations, in particular as a vaccine. The antigen is covalently bound to a component of the microvesicles envelope. The microvesicles of the invention, comprising a molar excess of fatty acids in the stabilizing envelope, are particularly effective in the uptake by antigen-presenting cells, in particular dendritic cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.